Abstract Background Surveillance of Over-the-Counter pharmaceutical (OTC) sales as a potential early indicator of developing public health conditions, in particular in cases of interest to biosurvellance, has been suggested in the literature.This paper is a continuation of a previous study in which we formulated the problem of estimating clinical d
Approximately 60% of morphine is glucuronidated to morphine-3-glucuronide (M3G) which may aggravate preexisting pain conditions.Accumulating evidence indicates that M3G signaling through neuronal Toll-like receptor 4 (TLR4) may be central to this proalgesic signaling event.These events are known to include elevated neuronal excitability, increased
The Internet of Things (IoT) generates lots of high-dimensional sensor intelligent data.The processing of high-dimensional data (e.g., data visualization and data classification) is very difficult, so it requires excellent subspace learning algorithms to learn a latent subspace to preserve the intrinsic structure of the high-dimensional data, and F
Urban growth needs large cities, and the current emphasis on landscape preservation makes using underground spaces an opportunity and a significant necessity.However, underground construction techniques significantly impact the sustainability of the built environment, including infrastructure systems and their entire supply chains.Nowadays, there i
This paper presents a site-specific seismic hazard study to determine the recommended seismic design criteria for Suramadu Bridge.The study is performed using probabilistic seismic hazard approach to determine maximum acceleration and response spectra at bedrock and followed by local site effect analysis to determine maximum acceleration and respon